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. 2015 Dec 23;68(1):120–130. doi: 10.1080/01635581.2016.1115094

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© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

© 2016 Anupam Bishayee, Animesh Mandal, Piyali Bhattacharyya, and Deepak Bhatia

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 3. — Quantitative analysis of mammary tumor cell proliferation and apoptosis during 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinogenesis in rats in the presence or absence of pomegranate emulsion (PE). Effects of PE on intra-tumor PCNA LI as determined by immunohistochemistry (A) and apoptotic index (AI) as measured by DNA fragmentation assay (B). The labeling index (LI) or AI was expressed as the number of immunopositive cells 100×/total number of tumor cells analyzed. Results are expressed as mean ± SEM (n = 4). *P < 0.001 compared with DMBA control.