Figure 5. Transthyretin aggregates in the synovial fluid of juvenile idiopathic arthritis.
Western blot analysis of transthyretin (TTR) proteins present in the synovial fluid of controls and juvenile idiopathic arthritis (JIA) patients run on a (A) native gel or (B) SDS-PAGE (representative gel out of 2 runs). TTR monomers (15 kDa), dimers (30 kDa), tetramers (60 kDa), and aggregates (above 60 kDa) are visible in JIA patients when run on a native gel. The patient ID for each lane is reported in Supplemental Figure 5.
