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. 2016 Mar 9;11(3):e0150858. doi: 10.1371/journal.pone.0150858

Table 8. Gene Set Enrichment Analysis (GSEA) categories enriched (FDR-adjusted P-value < 0.01, > 10 transcript isoforms) among transcript isoforms under-expressed in microglia relative to peripheral macrophages in BCG-challenged mice.

Category NG1 P-value FDR2
Adaptive immune response 21 <0.1E-05 <0.1E-05
Adaptive immune response 20 <0.1E-05 <0.1E-05
Positive regulation of immune response 20 <0.1E-05 <0.1E-05
Regulation of immune response 22 <0.1E-05 <0.1E-05
Regulation of immune system process 46 <0.1E-05 1.05E-03
Chemokine receptor binding 28 <0.1E-05 1.18E-03
Positive regulation of immune system process 37 <0.1E-05 1.34E-03
Positive regulation of response to stimulus 27 <0.1E-05 1.57E-03
KEGG primary immunodeficiency 30 <0.1E-05 1.88E-03
KEGG ribosome 81 <0.1E-05 1.90E-03
Regulation of lymphocyte activation 28 <0.1E-05 2.07E-03
Cellular defense response 38 <0.1E-05 2.28E-03
Lymphocyte activation 47 <0.1E-05 3.78E-03
G protein coupled receptor binding 35 <0.1E-05 4.34E-03
Chemokine activity 27 <0.1E-05 4.62E-03
Positive regulation of multicellular organismal process 47 <0.1E-05 4.63E-03
Cytokine activity 61 <0.1E-05 6.65E-03
B cell activation 18 <0.1E-05 7.59E-03
Locomotory behavior 61 <0.1E-05 8.08E-03
Leukocyte activation 51 <0.1E-05 8.95E-03
KEGG hematopoietic cell lineage 52 <0.1E-05 9.40E-03

1 NG: number of genes.

2 FDR: adjusted P-value.