Table 9. Genes exhibiting an alternative splicing event between microglia and macrophages in BCG-challenged mice including at least nine transcript isoforms and at least two over- or under-expressed (FDR-adjusted P-value < 0.05) transcript isoforms between cell types.
| Gene | NCBI Gene Name | Differential Expression | ||
|---|---|---|---|---|
| Under1 | Over2 | Non3 | ||
| Macf1 | microtubule-actin crosslinking factor 1 | 6 | 10 | 15 |
| Rbm5 | RNA binding motif protein 5 | 6 | 9 | 14 |
| Bag6 | BCL2-associated athanogene 6 | 7 | 7 | 13 |
| Arhgef1 | Rho guanine nucleotide exchange factor (GEF) 1 | 7 | 7 | 11 |
| Rbm39 | RNA binding motif protein 39 | 6 | 7 | 12 |
| Gapvd1 | GTPase activating protein and VPS9 domains 1 | 7 | 5 | 11 |
| Josd2 | Josephin domain containing 2 | 4 | 7 | 10 |
| Lrrc16a | leucine rich repeat containing 16A | 6 | 5 | 9 |
| Rnf220 | ring finger protein 220 | 2 | 8 | 9 |
| Gripap1 | GRIP1 associated protein 1 | 6 | 4 | 9 |
| Anapc1 | anaphase promoting complex subunit 1 | 5 | 5 | 9 |
| Arhgap4 | Rho GTPase activating protein 4 | 2 | 8 | 9 |
| Hnrnpl | heterogeneous nuclear ribonucleoprotein L | 4 | 6 | 9 |
| Il15ra | interleukin 15 receptor, alpha chain | 5 | 5 | 9 |
| Srsf5 | serine/arginine-rich splicing factor 5 | 3 | 7 | 8 |
| Ythdc1 | YTH domain containing 1 | 3 | 6 | 8 |
| Brwd1 | bromodomain and WD repeat domain containing 1 | 4 | 5 | 8 |
| Rtn4 | reticulon 4 | 4 | 5 | 8 |
| Sfrs18 | PNN interacting serine/arginine-rich | 4 | 5 | 8 |
| Wdr13 | WD repeat domain 13 | 5 | 4 | 8 |
| Wnk1 | WNK lysine deficient protein kinase 1 | 5 | 4 | 7 |
| Ctage5 | CTAGE family, member 5 | 3 | 6 | 6 |
| Hivep3 | human immunodeficiency virus type I enhancer binding protein 3 | 4 | 5 | 5 |
1Over: transcript isoforms over-expressed in microglia.
2Under: transcript isoforms under-expressed in microglia.
3Non: not differentially expressed transcript isoforms (FDR-adjusted P-value < 0.05).