Table 1. Demographic and Clinical Characteristics of Participants.
| Age | Female number | Years of education* | Total gray matter volume [ml]* | HAMD total score | |||
|---|---|---|---|---|---|---|---|
| mean (sd) | mean (sd) | mean (sd) | mean (sd) | ||||
| ALL | HS | 41.2 (11.4) | 13 | 16.6 (3.0) | 698.9 (61.4) | - (-) | |
| (n = 48) | |||||||
| MDD | 44.3 (13.0) | 13 | 13.4 (2.5) | 669.2 (64.9) | 7.7 (5.1) | ||
| (n = 30) | |||||||
| G1287A | HS | G/G (n = 27) | 40.3 (9.1) | 6 | 16.7 (2.9) | 711.6 (66.3) | - (-) |
| (n = 48) | |||||||
| A/- (n = 21) | 42.2 (14.0) | 7 | 16.3 (3.1) | 682.5 (51.5) | - (-) | ||
| G/A = 17, A/A = 4] | |||||||
| MDD | G/G (n = 12) | 41.0 (11.7) | 4 | 12.8 (1.8) | 644.4 (41.8) | 7.8 (4.0) | |
| (n = 30) | |||||||
| A/- (n = 18) | 47.6 (13.4) | 9 | 13.8 (2.9) | 656.6 (72.8) | 7.6 (6.0) | ||
| [G/A = 13, A/A = 5] | |||||||
| T-182C | HS | T/T (n = 27) | 42.8 (10.3) | 4 | 16.5 (2.2) | 713.2 (40.7) | - (-) |
| (n = 48) | |||||||
| C/- (n = 21) | 40.3 (12.7) | 9 | 16.5 (3.8) | 680.4 (66.9) | - (-) | ||
| [T/C = 17, C/C = 4] | |||||||
| MDD | T/T (n = 11) | 46.3 (13.9) | 5 | 13.2 (3.0) | 661.1 (73.1) | 5.5 (3.4) | |
| (n = 30) | |||||||
| C/- (n = 19) | 44.2 (12.7) | 8 | 13.5 (2.3) | 673.8 (61.2) | 8.9 (5.6) | ||
| [T/C = 10, C/C = 9] | |||||||
Abbreviations: sd = standard deviation; HS = healthy subjects; MDD = Major depression disorders; HAMD = 17-item Hamilton Rating Scale for Depression; G = Guanine; A = Adenine; T = Thymine; C = Cytosine.
*There was a significant difference between HS and MDD (p < 0.01).