FIG. 7.

Effect of G25 on the activity of purified recombinant P. falciparum Psd1 enzyme. P. falciparum Psd1 activity was determined as described in Materials and Methods by measuring the amount of [¹⁴C]phosphatidylethanolamine (PtdEtn) formed from phosphatidylserine (PtdSer). (A) Thin-layer chromatography analysis of P. falciparum Psd1-mediated conversion of phosphatidylserine into phosphatidylethanolamine in the absence and presence of increasing concentrations of G25. (B) Quantitative analysis of the thin-layer chromatography data shown in panel A. Values are means ± standard deviation of triplicate determination of two independent experiments.