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. 2016 Mar 9;11(3):e0150864. doi: 10.1371/journal.pone.0150864

Table 1. Proportions of each study design in 1998 and 2013.

1998 2013
Types of study Including transplant studies Excluding transplant studies Including transplant studies Excluding transplant studies
Less appropriate study designs as per the IDEAL recommendations
Overall 1620 (89%) 1419 (89.8%) 3497 (85.3%) 2941 (85.2%)
Case Studies 710 (39%) 661 (41.8%) 1318 (32.1%) 1222 (35.4%)
Retrospective case series or retrospective cohort study 856 (47%) 712 (45%) 2046 (49.9%) 1615 (46.8%)
Case-Control Study 54 (3%) 46 (2.9%) 133 (3.2%) 104 (3.0%)
More appropriate study designs as per the IDEAL recommendations
Overall 195 (10.7%) 156 (9.8%)# 498 (12.1%) 410(11.9%)#
Prospective Cohort Studies 137 (7.5%) 110 (7%) 388 (9.5%) 316 (9.2%)
Randomised Controlled Trials 32 (1.8%) 29 (1.8%) 71 (1.7%) 65 (1.9%)
Long-term follow-up 26 (1.4%) 17 (1.1%) 39 (1.0%) 29 (0.8%)
Not classified in IDEAL recommendations
Systematic Review 6 (0.3%) 6 (0.4%) 105 (2.6%) 102 (2.9%)
Total 1821 1581 4100 3453

#Difference in proportion utilising appropriate study designs = 2.3% (95% CI 0.5%-4%, p = 0.017). Comparison made excluding transplant studies