Figure 1.
Top panel: Structural illustration of dendrimeric molecules for BIRDS. Paramagnetic bifunctional chelates (isothiocyanate linked TmDOTA−) were conjugated onto the primary amines of PAMAM dendrimers (up to 4th generation). Bottom panel: NMR spectra of (M) Monomer (i.e. TmDOTA−), (G1) G1-PAMAM-(TmDOTA−)6, (G2) G2-PAMAM-(TmDOTA−)12, (Rhodamine-G2) Rhodamine-G2-PAMAM-(TmDOTA)12, (G3) G3-PAMAM-(TmDOTA−)25, (G4) G4-PAMAM-(TmDOTA−)39 at 35 °C and pH 7.4.