Table 3.
Efficacy of peri-coital FTC/TDF against vaginal SHIV infection
Regimen (number of FTC/TDF pills)* | Model characteristics | N. of animals infected |
---|---|---|
| ||
24h before/2h after (1:1) | Pigtails with regular menstrual cycles | 0/6, p<0.001 |
24h before/2h after (1:1) | Pigtails treated with a physiologic DMPA dose | 0/6, p<0.001 |
24h before/2h after (1:1) | Pigtails co-infected with C trachomatis and T vaginalis | 2/6, p = 0.03 |