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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Neurobiol Dis. 2016 Feb 11;89:202–212. doi: 10.1016/j.nbd.2016.02.011

Figure 5. MiR-210-LNA improved long-term neurological function recovery after neonatal HI brain injury.

Figure 5

Rat pups received via i.c.v. the negative control (Neg. Ctrl) or miR-210-LNA (LNA) 4 hours after the HI treatment, and neurological function was evaluated six weeks after HI. (A-C) Water maze tests of cued training (A), spatial leaning (B) and spatial memory (C). (D) Rotarod tests. Ctrl, sham control without HI. (E) Brain cortex width index analysis. n=9. * P<0.05, LNA vs. Neg. Ctrl. (F) Regression analysis of the correlation between the rotarod performances and cortex width index.