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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Clin Trials. 2015 Sep 22;13(2):161–168. doi: 10.1177/1740774515602688

Table 1.

Mean μ̃2 and variance σ22 of the observed/imputed values at year 2, and the probability that a one-sample one-sided test of H0: μ2 = 0 would be nominally statistically significant at the 0.05 level, for given mean and variance of the 1 and 2-year values (μ1, σ12, μ2, σ22), with a sample size of n = 100, 30% of which are missing completely at random at 2-years and are replaced by the values at 1-year. Cases 1 and 5 also provide the type I error probability and power with no missing data.

Case μ2
σ22
μ1
σ12
μ̃2
σ22
Pr(significant)
1 0 20 0 20 0 20 0.05
2 0 20 −1 20 −0.3 20.21 0.010
3 0 20 1 20 0.3 20.21 0.164
4 0 20 1 30 0.3 23.21 0.153
5 1 20 1 20 1 20 0.723
6 1 20 −1 20 0.4 20.84 0.221
7 1 20 0 20 0.7 20.21 0.465
8 1 20 2 20 1.3 20.21 0.894
9 1 20 2 30 1.3 23.21 0.854