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. 2016 Mar 10;7:300. doi: 10.3389/fmicb.2016.00300

FIGURE 4.

FIGURE 4

Dynamic role of filopodia connecting neurons influencing HSV-1 infections and associated inflammation. Virus travel either intracellular (a) or extracellular (b) between the cells. The diversity of HS chain in terms of sulfation pattern and chain length play a crucial role in interactions with cell surface molecules including leucocytes and soluble inflammatory cytokines.