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. 2004 Aug;48(8):2905–2910. doi: 10.1128/AAC.48.8.2905-2910.2004

TABLE 4.

Inhibition profiles of GES-type β-lactamases

Inhibitor IC50 (μM)
GES-4 GES-3 GES-2a GES-1a,b IBC-1c
Clavulanic acid 15 ± 1.7 1.5 ± 0.15 1.0 ± 0.5 5.0 1.1
Sulbactam 15 ± 0.9 0.91 ± 0.10 —d — —
Tazobactam 1.4 ± 0.31 0.19 ± 0.03 0.5 ± 0.2 2.5 0.12
Imipenem 2.1 ± 0.16 0.10 ± 0.01 8 ± 2 0.1 0.06
a

Data were reported in reference 25.

b

Data were reported in reference 21.

c

Data were reported in reference 8.

d

—, data not provided in the references.