Table 2.
Results of ICSI and IMSI cycles after two previous ICSI failures
| ICSI group | IMSI group | Statistical comparison | |
|---|---|---|---|
| Number of cycles | 127 | 89 | |
| Ovarian stimulation protocol | |||
| Long agonist | 31 (24 %) | 22 (25 %) | NS |
| Antagonist | 96 (76 %) | 67 (75 %) | |
| Total injected FSH units | 2085 ± 1021 | 2010 ± 833 | NS |
| No. follicles ≥15 mm (at last US monitoring) | 7.3 ± 2.5 | 7.5 ± 2.9 | NS |
| No. metaphase II ovocytes | 6.9 ± 3.1 | 8.1 ± 3.6 | P < 0.01 |
| Fertilization rate (%) | 61 ± 26 | 54 ± 24 | P < 0.05 |
| No. embryos obtained | 4.3 ± 2.6 | 4.5 ± 2.8 | NS |
| % of good morphology embryos (score 3 and 4, Giorgetti classification) | 32 ± 30 | 36 ± 35 | NS |
| No. embryo transfers | 119 (94 %) | 86 (97 %) | NS |
| No. transferred embryos | 2.3 ± 0.8 | 2.3 ± 0.8 | NS |
| Clinical pregnancy rate per oocyte retrieval | 28 % (35/119) | 27 % (24/89) | NS |
| Implantation rate | 10 % (28/270) | 12 % (23/194) | NS |
| Ongoing pregnancy rate | 21 % (25/119) | 23 % (20/86) | NS |
| Delivery rate per embryo transfer | 19 % (23/119) | 20 % (17/86) | NS |
| Cycles with frozen embryo (% per transfer) | 19 % (23/119) | 22 % (19/86) | NS |
| Number of frozen embryos per freezing | 2.3 ± 1.0 | 1.9 ± 0.7 | NS |