Table 3.

A: C-index analysis of with and without the addition of BSI to blood based biomarkers at baseline. B: C-index analysis of change in BSI and PSA at treatment follow-up

	C-index	Confidence interval	SE
A. Baseline analysisa (dead/total = 56/80)
BSI	0.71	0.64–0.77	0.03
PSA	0.65	0.57–0.72	0.03
ALP	0.67	0.58–0.75	0.03
HgB	0.26	0.20–0.32	0.03
PSA + ALP + HgB	0.67	0.58–0.74	0.03
PSA + ALP + HgB + BSI	0.72	0.64–0.78	0.03
B. Change (∆) at week 12 (dead/total = 40/62)
∆ BSI	0.75	0.68–0.81	0.05
∆ PSA	0.73	0.66–0.78	0.05
∆ PSA + ∆ BSI	0.77	0.71–0.82	0.05

^aBSI, PSA, ALP, and HgB values were observed skewed and therefore logarithmically transformed