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. 2015 Dec 14;23:218–234. doi: 10.1007/s12350-015-0344-8

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Example of global [¹²³I]MIBG H/M ratio and wash-out rate calculation on planar [¹²³I]MIBG imaging (A), and examples of normal cardiac [¹²³I]MIBG activity in a patient with H/M ratio of 1.80 (B) compared with a [¹²³I]MIBG scan showing a significantly impaired [¹²³I]MIBG activity with H/M ratio of 1.10 (C). H/M, heart-to-mediastinum. Reprint with permission70