Figure 4.
Kuijie Granule increases the expression of Smad4 and decreases Smad7 in colon tissue of patients with UC. (a) and (b) show the data analysis results for Smad4 and Smad7 expression; there exist significant differences before and after Kuijie Granule treatment (∗∗ P < 0.01); n = 72. ICH Histological Score means the integration of patients in Smad4 and Smad7 expression which come from the percentage of positive cells, 1 point: 0~10%, 2 points: 11%~25%, 3 points: 26%~75%, and 4 points: 76%~100%. (c) Representative images of the microscopic images obtained from colon tissues of patients with UC staining with anti-Smad4 and anti-Smad7.