. 2016 Mar 10;6:22760. doi: 10.1038/srep22760

Table 1. Mutation analysis of VDJ region in Mef^−/− Rad50^s/s plasma cell tumor samples.

Mice UID	Tumor	V_H	D_H	J_H	No.Mutationsat V_H	Mutations atV_H andAmion Acid Changes	Percent Mutationsat V_H
33	MM	IGHV1-50^01, IGHV1-59^01 or IGHV1S40^*01	IGHD2-3^*01	IGHJ4^*01	1	c227 > g, A76 > G	1.0
112	MM	IGHV1-67^*01	IGHD4-1^*01	IGHJ3^*01	2	c227 > g, A76 > G a232 > t, M78 > L	2.1
217	PCT	IGHV1-67^*01	IGHD3-2^*02	IGHJ3^*01	7	c227 > g, A76 > G	7.3
						a232 > t, M78 > L
						g25 > c, S85 > T
						a256 > t, T86 > S
						a263 > t, Y88 > F
						a290 > g, E97 > G
						g291 > a, E97 > G

The first two columns show mouse UID and the phenotype of the mice (MM, multiple myeloma; PCT, solitary plasmacytoma). The V_H, D_H, and J_H usage and mutations were scored by comparing each sequence with the germline sequences at the IMGT server.

Table 1. Mutation analysis of VDJ region in Mef−/− Rad50s/s plasma cell tumor samples.

Table 1. Mutation analysis of VDJ region in Mef^−/− Rad50^s/s plasma cell tumor samples.