Table 2. Diagnostic performance (with 95% confidence intervals) derived from the 2 × 2 tables of individual studies.
| Authors | Year | TP | FN | FP | TN | Inadequate/AS | Sensitivity | Specificity | PLR | NLR | DOR |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Ramesh J | 2015 | 41 | 2 | 0 | 7 | 4/0 | 95(84–99) | 100(59–100) | 15.1(1.0–221.2) | 0.06(0.02–0.21) | 249.0(10.8–5720.6) |
| Berzosa M | 2015 | 28 | 12 | 0 | 21 | 16/0 | 70(54–83) | 100(84–100) | 30.6(2.0–477.3) | 0.31(0.20–0.50) | 98.0(5.5–1749.3) |
| Fabbri C | 2015 | 48 | 0 | 0 | 20 | 10/4 | 100(93–100) | 100(83–100) | 41.6(2.7–643.0) | 0.01(0.00–0.17) | 3977.0(76.3–207333.1) |
| Lee Y | 2014 | 54 | 3 | 0 | 1 | 0/0 | 95(85–99) | 100(2.5–100) | 3.8(0.3–41.5) | 0.08(0.02–0.29) | 46.7(1.6–1369.5) |
| Vanbiervliet G | 2014 | 65 | 5 | 1 | 9 | 9/0 | 93(84–98) | 90(56–100) | 9.3(1.4–59.7) | 0.08(0.03–0.19) | 117.0(12.2–1118.3) |
| Iwashita T | 2013 | 44 | 2 | 0 | 4 | 0/0 | 96(85–99) | 100(40–100) | 9.5(0.7–131.4) | 0.06(0.02–0.20) | 160.2(6.6–3880.9) |
| Hucl T | 2013 | 59 | 5 | 0 | 5 | 5/0 | 92(83–97) | 100(48–100) | 11.0(0.8–156.2) | 0.09(0.04–0.21) | 119.0(5.8–2448.2) |
| Larghi A | 2013 | 49 | 7 | 0 | 5 | 7/0 | 88(76–95) | 100(48–100) | 10.4(0.7–148.4) | 0.14(0.07–0.29) | 72.6(3.6–1451.2) |
| Krishnan K | 2013 | 17 | 4 | 0 | 2 | NA | 81(58–95) | 100(16–100) | 4.8(0.4–60.5) | 0.25(0.09–0.65) | 19.4(0.8–481.0) |
| Bang J | 2012 | 22 | 3 | 0 | 3 | 1/0 | 88(69–98) | 100(29–100) | 6.9(0.5–93) | 0.15(0.05–0.43) | 45.0(1.9–1071.3) |
| Varadarajulu S | 2012 | 25 | 0 | 1 | 6 | 3 | 100(86–100) | 86(42–100) | 5.2(1.2 –22.1) | 0.02(0.01–0.38) | 221.0(8.0–6079.1) |
| Iglesias J | 2011 | 42 | 3 | 0 | 2 | 2/0 | 93(82–99) | 100(16–100) | 5.5(0.4–69.7) | 0.09(0.03–0.28) | 60.7(2.4–1528.8) |
| Sakamoto H | 2009 | 9 | 12 | 0 | 3 | 12/0 | 43(22–66) | 100(29–100) | 3.5(0.2–48.3) | 0.65(0.39–1.09) | 5.3(0.2–115.9) |
| Thomas T | 2009 | 63 | 38 | 0 | 12 | NA | 62(52–72) | 100(74–100) | 16.2(1.1–246.3) | 0.39(0.30–0.52) | 41.2(2.4–716.4) |
| Yun SS | 2007 | 25 | 11 | 1 | 15 | 0/5 | 69(52–84) | 94(70–100) | 11.1(1.6–75.0) | 0.33(0.20–0.54) | 34.1(4.0–291.2) |
| Ginès A | 2005 | 7 | 4 | 0 | 1 | 2/0 | 64(31–89) | 100(2.5–100) | 2.5(0.2–28.7) | 0.50(0.17–1.48) | 5.0(0.2–150.9) |
| Overall | 598 | 111 | 3 | 116 | 84(82–87) | 98(93–100) | 8.0(4.5–14.4) | 0.17(0.10–0.26) | 64.0(30.4–134.8) | ||
FN, false negative; FP, false positive; TN, true negative; TP, true positive; Inadequate/AS, inadequate tissue or technical failure/ atypical or suspicious; PLR, positive likelihood ratio; NLR, negative likelihood ratio; DOR, diagnostic odds ratio; NA, not available.