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. 2016 Mar 10;6:22845. doi: 10.1038/srep22845

Figure 4. Cytokine secretion profiles of DC-peripheral blood mononuclear cell (PBMC) co-cultures.

Figure 4

Cytokine production levels of co-cultures of autologous PBMCs and monocyte-derived DCs (n ≥ 4) pre-stimulated 24 hours with LGG conditioned medium (CM); or LGG conditioned medium with LGG cells (CM + LGG); or 1000 U/ml recombinant human (rh) IFNγ, 1000 ng/ml lipopolysaccharides (LPS) and 1 μg/ml R848 (positive control; Pos); or alone (negative control; Neg) were analyzed by multiplex assay. Results are shown as mean ± SD. *p < 0.05, **p < 0.01 and ***p < 0.001 in comparisons between treated cells and negative control. #p < 0.05, ##p < 0.01 and ###p < 0.001 in comparisons between CM-treated and CM + LGG-treated cells.