. 2016 Mar 10;3(1):ENEURO.0138-15.2016. doi: 10.1523/ENEURO.0138-15.2016

Table 2.

Baseline ratings

	Slow pleasantness	Fast pleasantness	Slow intensity	Fast intensity
Healthy volunteers
Naloxone Saline	4.63 ± 3.73 4.05 ± 3.42 t₍₂₆₎ = 0.43, p = 0.67	3.31 ± 3.70 1.42 ± 3.21 t₍₂₆₎ = 1.45, p = 0.16	1.34 ± 0.62 1.53 ± 0.79 t₍₂₆₎ = 0.72, p = 0.48	2.13 ± 0.89 2.42 ± 0.75 t₍₂₆₎ = 0.93, p = 0.36
Chronic pain (FM) patients
Naloxone Saline	2.30 ± 3.11 3.19 ± 5.00 t₍₂₂₎ = 0.51, p = 0.62	1.80 ± 3.85 3.54 ± 2.85 t₍₂₂₎ = 1.27, p = 0.22	1.50 ± 0.75 2.05 ± 0.97 t₍₂₂₎ = 1.50, p = 0.15	2.21 ± 0.60 2.08 ± 0.80 t₍₂₂₎ = 0.46, p = 0.65

Healthy participants and FM patients rated the pleasantness and intensity of slow (CT-optimal) and fast brushing of the left forearm on the corresponding VAS scales. Mean ratings ± SD at baseline (before any drug administration) are displayed for slow and fast brushing for the naloxone and saline groups for healthy participants and FM patients. The t tests show that before drug infusion, there were no significant differences in ratings between individuals who subsequently received naloxone versus saline.