TABLE 1.

Mutations detected in the pncA gene of PZA-resistant M. tuberculosis isolates

No. (%) of isolates	Change(s) in:
	Nucleotide sequencea	Amino acidb
5 (18)	A→C at position 226	T76→P
5 (18)	T→C at position 307	Y103→H
2	A→G at position 188	D63→G
2	C→D at position 216	C72→W
2	T→G at position 254	L85→R
1	C→T at position 28	Q10→Ter
1	G→A at position 41	C14→Y
1	C→A at position 184	P62→T
1	A→T at position 308	Y103→S
1	G→A at position 413	C138→Y
1	G→T at position 537	V180→F
1	WT/C→G at position 42 + T→C at position 307	WT/C14→W + Y103→H
5 (18)	WT	WT

^aWT, wild type.

^bTer, chain synthesis-terminating codon.