TABLE 2.
Cytokine or chemokine | Correlation with:
|
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
M. pneumoniae cultures
|
HPS
|
AOa
|
AHRb
|
Cethromycin therapy
|
|||||||||||
r | P | n | r | P | n | r | P | n | r | P | n | r | P | n | |
IL-1β | 0.2 | 0.4 | 15 | 0.5 | 0.05 | 19 | 0.3 | 0.2 | 16 | 0.6 | 0.02 | 16 | −0.5 | 0.03 | 19 |
IL-2 | 0.3 | 0.3 | 15 | 0.5 | 0.01 | 19 | 0.4 | 0.2 | 16 | 0.4 | 0.1 | 16 | −0.4 | 0.09 | 19 |
TNF-α | 0.2 | 0.3 | 19 | 0.7 | <0.001 | 23 | 0.4 | 0.09 | 20 | 0.3 | 0.2 | 20 | −0.6 | 0.005 | 23 |
IL-12 | 0.5 | 0.06 | 15 | 0.5 | 0.02 | 19 | 0.6 | 0.01 | 16 | 0.4 | 0.2 | 16 | −0.7 | 0.002 | 19 |
IFN-γ | 0.7 | 0.004 | 15 | 0.7 | <0.001 | 19 | 0.7 | <0.001 | 16 | 0.6 | 0.01 | 16 | −0.6 | 0.008 | 19 |
IL-4 | 0.03 | 0.9 | 15 | 0.4 | 0.1 | 19 | 0.3 | 0.2 | 16 | 0.4 | 0.1 | 16 | −0.1 | 0.5 | 19 |
GM-CSF | 0.02 | 0.9 | 15 | 0.3 | 0.1 | 19 | 0.08 | 0.7 | 16 | 0.3 | 0.2 | 16 | 0.05 | 0.8 | 19 |
IL-8 | 0.2 | 0.4 | 19 | 0.3 | 0.1 | 23 | 0.4 | 0.1 | 20 | 0.4 | 0.04 | 20 | −0.4 | 0.003 | 23 |
MCP-1 | 0.3 | 0.3 | 19 | 0.6 | 0.001 | 23 | 0.6 | 0.005 | 20 | 0.4 | 0.07 | 20 | −0.8 | <0.001 | 23 |
MIP-1α | 0.2 | 0.3 | 19 | 0.6 | 0.007 | 22 | 0.5 | 0.05 | 19 | 0.2 | 0.3 | 19 | −0.8 | <0.001 | 22 |
AO, airway obstruction.
AHR, airway hyperreactivity.