Table 3. Genotype, allele frequencies and Hardy–Weinberg Χ2 in the NAT2 gene among six Indian populations.
| Populations |
Genotype
|
MAF |
HWE
|
|||
|---|---|---|---|---|---|---|
| CC | CT | TT | rs1799929 (T) | HW χ2 | HW p | |
|
rs1799929
| ||||||
| Reddy | 22 (47.83) | 18 (39.13) | 6 (13.04) | 0.326 | 0.553 | 0.457 |
| Sugali | 12 (44.44) | 14 (51.85) | 1 (3.70) | 0.296 | 1.599 | 0.206 |
| Balija | 17 (50.0) | 11 (32.35) | 6 (17.65) | 0.338 | 2.614 | 0.106 |
| Muslim | 21 (48.84) | 16 (37.21) | 6 (13.95) | 0.326 | 1.003 | 0.317 |
| Mala | 22 (48.89) | 19 (42.22) | 4 (8.89) | 0.300 | 0.001 | 0.972 |
| Madiga | 10 (58.82) | 6 (35.29) | 1 (5.88) | 0.235 | 0.006 | 0.937 |
| GG | GA | AA | rs1799930 (A) | HW χ 2 | HW p | |
|
rs1799930
| ||||||
| Reddy | 17 (36.96) | 20 (43.48) | 9 (19.57) | 0.413 | 0.491 | 0.484 |
| Sugali | 9 (33.33) | 12 (44.44) | 6 (22.22) | 0.444 | 0.270 | 0.603 |
| Balija | 16 (47.06) | 15 (44.12) | 3 (8.82) | 0.309 | 0.038 | 0.845 |
| Muslim | 15 (34.88) | 18 (41.86) | 10 (23.26) | 0.442 | 0.985 | 0.321 |
| Mala | 21 (46.67) | 16 (35.56) | 8 (17.78) | 0.356 | 2.261 | 0.133 |
| Madiga | 6 (35.29) | 9 (52.94) | 2 (11.76) | 0.382 | 0.248 | 0.618 |
| rs1799931 (A) | ||||||
|
rs1799931
| ||||||
| Reddy | 42 (91.3) | 4 (8.7) | 0 (0.0) | 0.043 | 0.095 | 0.758 |
| Sugali | 25 (92.59) | 2 (7.41) | 0 (0.0) | 0.037 | 0.040 | 0.842 |
| Balija | 32 (94.12) | 2 (5.88) | 0 (0.0) | 0.030 | 0.031 | 0.859 |
| Muslim | 38 (88.37) | 4 (9.3) | 1 (2.33) | 0.070 | 3.452 | 0.063 |
| Mala | 36 (80.0) | 9 (20.0) | 0 (0.0) | 0.100 | 0.556 | 0.456 |
| Madiga | 13 (76.47) | 4 (23.53) | 0 (0.0) | 0.118 | 0.302 | 0.583 |
Abbreviations: HWE, Hardy–Weinberg equation; HW p, Hardy–Weinberg P value; MAF, minor allele frequency. d.f.=1 for all tests.