Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 2;2:15009. doi: 10.1038/hgv.2015.9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 The Japan Society of Human Genetics

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

PMC Copyright notice

Correlation of pathway activation profiles in CRC tumorgrafts and primary colorectal tumors and principal components analysis. Compared with normal colorectal tissue, significantly upregulated or downregulated pathways were identified based on PAS values (P value<0.05). The PAS values of tumorgrafts correlated significantly with the PAS values of primary colorectal cancer patients in all three cohorts tested: (GSE33113, a), (GSE21510, b) and (GSE44076, c). Principle component analyses (PCA) were performed to assess the variation and clustering between PAS of tumorgrafts and primary CRC patients (GSE44076), and the first three principal components are shown (d). Each sample is represented by one dot. Samples from tumorgrafts (red dots) and the primary CRC data set (GSE44076) (green dots) are overlaid. One set of lung cancer (GSE30219, blue dots) and melanoma (GSE7533, orange dots) samples were also plotted as references. The mean Euclidean distances between the colon cancer tumorgrafts group and the human colon cancer, lung cancer and melanoma groups are 41.43, 79.95 and 124.65, respectively.