Table 2. Filtering the called variants by exome sequencing.

	IV-14	IV-19	V-4	V-6
SNVs
Called SNVs	150,251	172,375	231,744	262,960
	↓	↓	↓	↓
And not in the dbSNP 132	7,485	10,607	14,995	12,969
	↓
And shared by all four individuals	194
	↓
And not in our in-house database, and heterozygous	7
	↓
And located within the F1 linkage regions (chr1, chr14, chr15 and chr17)	7
	↓
And located within the F2 linkage region (chr1q23.3-24.1)	1
INDELs
Called INDELs	62,860	60,479	58,671	75,259
	↓
And shared by all four individuals	5,125
	↓
And heterozygous	1,543
	↓
And located within the F1 linkage regions (chr1, chr14, chr15 and chr17)	21
	↓
And located within the F2 linkage region (chr1q23.3-24.1)	4