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. Author manuscript; available in PMC: 2016 Jun 17.
Published in final edited form as: J Am Chem Soc. 2015 Jun 4;137(23):7290–7293. doi: 10.1021/jacs.5b04289

Table 2.

Aryl boronic acid scope.

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Standard reaction conditions: 1 (0.75 mmol, 3.0 eq), 2a (0.25 mmol, 1.0 eq), Pd(MeCN)2(OTs)2 (0.019 mmol, 7.5 mol%), ligand (0.023 mmol, 9 mol%), DMA (3 mL), 3Å Ms (50 mg), O2 (1 atm), rt, 24 h. Yields are of isolated 3, >20:1 E-alkene product. Enantioselectivty determined by SFC equiped with a chiral stationary phase.

a

Cu(OTf)2 (0.013 mmol, 5 mol%), ligand (0.035 mmol, 14 mol%) were used.