Table 2.
Associations between BMI Trajectories in Relation to Relative Changes from Baseline to the 9 year Follow up in Body Composition and Physical Function
| MEN | WOMEN | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
|
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| n | Absolute | Relative | Model 1 | Model 2 | n | Absolute | Relative | Model 1 | Model 2 | |
| Body composition | ||||||||||
| Total appendicular lean mass (kg) | ||||||||||
| Trajectory 1 | 113 | −1.29±1.57 | −5.8±7.1 | reference | reference | 77 | −0.44±0.86 | −3.1±6.0 | reference | reference |
| Trajectory 2 | 191 | −1.36±1.53 | −5.6±6.3 | −0.40 (−1.90; 1.10) | −0.45 (−1.95; 1.06) | 183 | −0.61±1.09 | −3.9±7.1 | −0.89 (−2.79; 1.01) | −0.85 (−2.80; 1.11) |
| Trajectory 3 | 138 | −1.33±1.91 | −4.9±7.1 | 0.40 (−1.21; 2.01) | 0.31 (−1.31; 1.93) | 171 | −0.64±1.30 | −3.5±7.2 | −0.45 (−2.41; 1.51) | −0.38 (−2.42; 1.67) |
| Trajectory 4 | 40 | −1.34±2.33 | −4.3±8.1 | 1.04 (−1.27; 3.36) | 1.24 (−1.11; 3.60) | 85 | −0.78±1.64 | −3.7±8.5 | −0.35 (−2.65; 1.94) | −0.15 (−2.56; 2.26) |
| P-for trend | 0.902 | 0.180 | 0.278 | 0.224 | 0.079 | 0.663 | 0.865 | 0.997 | ||
| Lean mass in the arms (kg) | ||||||||||
| Trajectory 1 | 113 | −0.45±0.50 | −7.3±8.1 | reference | reference | 77 | −0.12±0.22 | −3.4±6.3 | reference | reference |
| Trajectory 2 | 191 | −0.50±0.51 | −7.3±7.4 | −0.87 (−2.52; 0.77) | −0.97 (−2.64; 0.70) | 183 | −0.17±0.36 | −4.1±9.5 | −0.94 (−3.28; 1.39) | −0.98 (−3.39; 1.42) |
| Trajectory 3 | 138 | −0.53±0.62 | −7.0±8.0 | −0.56 (−2.33; 1.20) | −0.55 (−2.35; 1.24) | 171 | −0.19±0.41 | −4.0±9.5 | −1.07 (−3.48; 1.34) | −1.15 (−3.67; 1.37) |
| Trajectory 4 | 40 | −0.63±0.74 | −7.5±9.5 | −0.90 (−3.44; 1.65) | −0.67 (−3.28; 1.94) | 85 | −0.33±0.49 | −6.3±10.1 | −3.07 (−5.89; −0.25) | −3.19 (−6.16; −0.23) |
| P-for trend | 0.073 | 0.984 | 0.550 | 0.698 | <0.001 | 0.052 | 0.038 | 0.040 | ||
| Lean mass in the legs (kg) | ||||||||||
| Trajectory 1 | 113 | −0.85±1.18 | −5.2±7.3 | reference | reference | 77 | −0.31±0.75 | −2.9±7.0 | reference | reference |
| Trajectory 2 | 191 | −0.86±1.17 | −4.9±6.7 | −0.22 (−1.85; 1.41) | −0.25 (−1.88; 1.39) | 183 | −0.45±0.85 | −3.8±7.3 | −0.88 (−2.93; 1.16) | −0.83 (−2.93; 1.28) |
| Trajectory 3 | 138 | −0.80±1.43 | −4.1±7.5 | 0.78 (−0.97; 2.54) | 0.66 (−1.10; 2.42) | 171 | −0.46±0.98 | −3.3±7.3 | −0.27 (−2.38; 1.84) | −0.16 (−2.36; 2.04) |
| Trajectory 4 | 40 | −0.72±1.77 | −3.1±8.4 | 1.79 (−0.72; 4.31) | 2.00 (−0.56; 4.56) | 85 | −0.45±1.40 | −2.8±9.6 | 0.46 (−2.01; 2.93) | 0.74 (−1.85; 3.34) |
| P−for trend | 0.542 | 0.074 | 0.105 | 0.085 | 0.395 | 0.858 | 0.613 | 0.483 | ||
| Physical function | ||||||||||
| Gait speed (m/s) | ||||||||||
| Trajectory 1 | 113 | −0.37±0.23 | −23.5±14.2 | reference | reference | 77 | −0.37±0.20 | −25.5±12.1 | reference | reference |
| Trajectory 2 | 191 | −0.43±0.24 | −27.3±13.6 | −4.00 (−7.33; −0.67) | −3.58 (−6.94; −0.23) | 183 | −0.33±0.21 | −23.6±14.5 | 1.49 (−2.43; 5.41) | 2.33 (−1.68; 6.34) |
| Trajectory 3 | 138 | −0.36±0.24 | −23.7±14.7 | −1.12 (−4.70; 2.46) | −0.77 (−4.36; 2.83) | 171 | −0.33±0.22 | −24.1±15.6 | 0.22 (−3.82; 4.27) | 1.20 (−3.00; 5.39) |
| Trajectory 4 | 40 | −0.50±0.26 | −33.4±17.4 | −11.11(−16.26; −5.97) | −9.91 (−15.15; −4.67) | 85 | −0.31±0.22 | −25.2±16.7 | −1.11 (−5.84; 3.62) | −0.24 (−5.18; 4.70) |
| P-for trend | 0.018 | 0.001 | <0.001 | 0.001 | 0.075 | 0.978 | 0.539 | 0.813 | ||
| Grip strength (kg) | ||||||||||
| Trajectory 1 | 113 | −6.87±6.30 | −16.3±16.5 | reference | reference | 77 | −2.94±4.31 | −9.4±26.0 | reference | reference |
| Trajectory 2 | 191 | −6.19±6.48 | −14.4±16.2 | 0.97 (−2.88; 4.81) | 0.49 (−3.45; 4.35) | 183 | 3.56±4.65 | −12.8±18.0 | −3.99 (−9.92; 1.95) | −3.02 (−9.08; 3.04) |
| Trajectory 3 | 138 | −5.70±6.97 | −12.6±17.3 | 2.54 (−1.59; 6.68) | 2.42 (−1.76; 6.62) | 171 | −2.98±5.28 | −9.0±26.6 | −1.28 (−7.40; 4.85) | −0.01 (−6.35; 6.34) |
| Trajectory 4 | 40 | −7.00±6.67 | −15.2±16.5 | 0.07 (−5.86; 6.01) | −0.01 (−6.07; 6.06) | 85 | −3.34±4.79 | −11.2±18.2 | −3.63 (−10.79;3.54) | −3.04 (−10.51;4.43) |
| P-for trend | 0.979 | 0.586 | 0.846 | 0.841 | 0.789 | 0.876 | 0.472 | 0.609 | ||
| Leg strength (Nm) | ||||||||||
| Trajectory 1 | 113 | −36.8±27.4 | −26.1±21.9 | reference | reference | 77 | −19.7±14.9 | −24.9±22.4 | reference | reference |
| Trajectory 2 | 191 | −35.5±29.2 | −24.0±19.9 | −0.07 (−4.49; 4.35) | −0.44 (−4.91; 4.03) | 183 | −19.0±18.1 | −20.9±23.3 | 3.21 (−3.30; 9.73) | 3.94 (−2.68; 10.56) |
| Trajectory 3 | 138 | −41.0±33.7 | −26.1±20.9 | −2.46 (−7.21; 2.29) | −2.40 (−7.20; 2.41) | 171 | −22.4±23.6 | −22.5±24.5 | 0.70 (−6.03; 7.42) | 1.41 (−5.52; 8.34) |
| Trajectory 4 | 40 | −56.0±52.4 | −32.8±20.9 | −8.59 (−15.42;−1.76) | −8.63 (−15.62;−1.64) | 85 | −24.5±23.8 | −23.0±33.2 | 1.09 (−6.78; 8.95) | 1.83 (−6.32; 9.99) |
| P-for trend | <0.001 | 0.060 | 0.009 | 0.011 | 0.078 | 0.741 | 0.953 | 0.819 | ||
Model 1 was adjusted for age, race, study site, and education.
Model 2 was adjusted for model 1 plus smoking status, physical activity, hypertension, diabetes, cardiovascular disease, heart failure, edema, and cancer.