Table 4.
Comparison of variables between the less invasive surfactant administration success and failure groups.
| LISA Failure N=13 | LISA Success N=17 | p (95% CI) | |
|---|---|---|---|
| Gestational age (weeks), mean(SD) | 27.4(1.61) | 29.1(2.02) | 0.02 |
| Birth weight (grams), mean(SD) | 992(387) | 1108 (397) | 0.263 |
| Prenatal corticosteroids, n(%) | 9(69.2) | 13(76.5) | 0.691 |
| Intubation at delivery, n(%) | 30.8 | 17.6 | 0.4 |
| Age at procedure (hours), mean(SD) | 8.4(9.6) | 13.7(17.7) | 0.7 |
| FiO2 before procedure, mean(SD) | 4.6(37.6) | 21.6(46) | 0.5 |
| FiO2 reduction after surfactant (>20%), n(%) | 6(46.2) | 16(94.1) | 0.003 |
| PPI during instillation, n(%) | 2(15.4) | 1(5.9) | 0.39 |
| PDA, % | 46 | 29.4 | 0.3 |
| Total iMV (hours), mean(SD) | 196.46(244) | 9.18(18.7) | 0.04 |
| Pneumothorax, n(%) | 2(15.4) | 0 | 0.09 |
| BPD (II-III), % | 30.8 | 25.6 | 0.907 |
LISA: less invasive surfactant administration.
BPD: bronchopulmonary dysplasia; iMV: invasive mechanical ventilation; PPI: positive pressure inflations; SD: standard deviation.