TABLE 2.
Well-Studied Methylated Genes in CRC and the Relevant References
| Gene symbol | Description | References |
|---|---|---|
| MLH1 | MutL Homolog 1 |
Kane, et al., 1997 Cunningham, et al., 1998 Weisenberger, et al., 2006 |
| BNIP3 | BCL2/Adenovirus E1B 19kDa Interacting Protein 3 |
Murai, et al., 2005 Shimizu, et al., 2010 Liu, et al., 2011 |
| CHFR | Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase |
Morioka, et al., 2006 Tanaka, et al., 2011 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
Nakamura, et al., 2001 Gerson 2004 Ogino, et al., 2007 Nagasaka, et al., 2008 Hibi, et al., 2009 Hawkins, et al., 2009 Lee, et al., 2009 |
| HLTF | Helicase-like transcription factor |
Moinova, et al., 2002 Herbst, et al., 2009 Sandhu, et al., 2012 |
| RBP1 | Retinol binding protein 1, cellular |
Esteller, et al., 2002 Toki, et al., 2010 Peralta, et al., 2012 |