Table 2. Incidence and Mortality of EAC after RFA in Patients with BE, by Baseline Histology.
| Baseline Histology | Patients n (%) | Patient- Years of Follow-up | Incident EAC Cases n | EAC Incidence per 1000 PY [95% CI] | Deaths from EAC n | EAC Mortality per 1000 PY [95% CI] | All-Cause Mortality n | All-Cause Mortality per 1000 PY [95% CI] | |
|---|---|---|---|---|---|---|---|---|---|
| Unadjusted | Adjusted‡ | ||||||||
| NDBE | 2346 (47) | 6348 | 3 | 0.5[0.1-1.4] | 0 | 0 [0-0.6] | 36 | 5.7 [4.0-7.9] | 6.4 [4.0-8.8] |
| IND | 368(7) | 967 | 2 | 2.1[0.3-7.6] | 0 | 0 [0-3.8] | 10 | 10.3 [5.0-19.0] | 10.6 [1.9-19.4] |
| LGD | 1020(21) | 2852 | 12 | 4.3[2.2-7.5] | 0 | 0 [0-1.3] | 26 | 9.1 [6.0-13.4] | 6.8 [3.4-10.1] |
| HGD | 990(20) | 2928 | 83 | 30.3[24.2-37.6] | 6 | 2.0 [0.8-4.5] | 60 | 20.5 [15.6-26.4] | 24.8[12.1-37.4] |
| Total, non-malignant | 4724(95) | 13095 | 100 | 7.8[6.4-9.5] | 6 | 0.5 [0.2-1.0] | 132 | 10.1 [8.4-12.0] | 11.5 [8.3-14.6] |
| Intramucosal EAC | 195(4) | 560 | -- | -- | 3 | 5.4[1.1-15.7] | 11 | 19.6 [9.8-35.2] | 27.1 [0.0-69.2] |
| Invasive EAC | 63(1) | 180 | -- | -- | 0 | 0 [0-20.5] | 14 | 77.9 [42.6-130.8] | 43.3[1.4-85.2] |
| Total | 4982 | 13835 | -- | -- | 9 | 0.7[0.3-1.2] | 157 | 11.3 [9.6-13.3] | 11.7 [9.0-14.5] |
‡
Age- and sex-adjusted to the 2010 US population age 45 and older.