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. 2016 Jan 26;26(4):1778–1794. doi: 10.1093/cercor/bhw002

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© The Author 2016. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 8. — Cell type-specific changes in sIPSCs in brain slices from Scn1a^−/+ mice. (A) Left: schematic of the experimental configuration. Recordings were performed from principal cortical neurons. Right: sIPSCs in slices from WT (top) and Scn1a^−/+ (bottom) animals recorded from principal neurons. (B) Cumulative distribution of the amplitude (left) and frequency (right) of sIPSCs recorded from WT (N = 8 cells) and Scn1a^−/+ (N = 8 cells). (C,D) and (E,F) same as in (A and B) for sIPSCs recorded from PV-positive (WT, N = 8 cells; Scn1a^−/+, N = 8 cells) and SST-positive (WT, N = 8 cells; Scn1a^−/+, N = 8 cells) interneurons, respectively.