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. 2016 Jan 26;26(4):1778–1794. doi: 10.1093/cercor/bhw002

Table 5.

Biophysical properties of recorded neurons

Principal cells
PV-positive cells
SST-positive cells
WT (N = 27 cells) Scn1a−/+ (N = 27 cells) WT (N = 21 cells) Scn1a−/+ (N = 28 cells) WT (N = 25 cells) Scn1a−/+ (N = 28 cells)
Rin (MΩ) 103 ± 9 107 ± 9 109 ± 8 86 ± 5* 208 ± 16 195 ± 14
AP amplitude (mV) 84 ± 2 85 ± 1 66 ± 2 63 ± 2 72 ± 2 71 ± 2
AP duration (ms) 1.04 ± 0.05 1.09 ± 0.04 0.36 ± 0.01 0.39 ± 0.01 0.65 ± 0.02 0.79 ± 0.04**
AP rise time (ms) 0.59 ± 0.03 0.59 ± 0.02 0.37 ± 0.01 0.40 ± 0.01* 0.56 ± 0.02 0.63 ± 0.02**
AP threshold (mV) −42.6 ± 0.7 −42.0 ± 0.8 −41.7 ± 1.1 −42.4 ± 0.9 −42.1 ± 0.8 −42.5 ± 0.7

Note: Statistical significance was evaluated with unpaired Student's t-test. *P < 0.05; **P < 0.01.