. Author manuscript; available in PMC: 2016 Mar 10.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2013 Dec 5;88(2):446–452. doi: 10.1016/j.ijrobp.2013.10.038

Table 2.

Dosimetric comparison showing advantage of predictive treatment planning in increasing dose to residual tumor without significantly increasing dose to lung and cord

	Patient	PTV_resid D95 (Gy)	PTV_resid D_min (Gy)	PTV_resid D_mean (Gy)	PTV_gone D95 (Gy)	Lung D_mean (Gy)	Lung NTCP	Cord D_max (Gy)
1	Clinical	61.5	53.2	62.7	60.6	19.3	0.23	43.0
	GTV boost	63.0	50.1	70.0	61.0	19.5	0.25	44.1
	Replan	63.9	56.3	66.6	61.1	19.7	0.25	42.8
	RPTP	64.1	54.9	72.6	59.3	19.8	0.25	44.0
2	Clinical	61.0	56.4	62.3	60.8	19.5	0.23	45.8
	GTV boost	63.6	59.1	69.6	62.0	19.7	0.25	46.0
	Replan	65.3	59.6	67.3	62.2	19.5	0.24	45.1
	RPTP	66.7	60.3	72.9	59.4	19.7	0.25	45.8
3	Clinical	70.3	69.4	71.4	70.3	18.3	0.15	41.9
	GTV boost	76.0	70.9	83.0	75.5	18.1	0.15	42.6
	Replan	79.7	73.2	81.1	75.1	18.2	0.15	40.6
	RPTP	81.6	74.8	89.7	74.5	18.0	0.15	42.3
4	Clinical	57.0	55.9	57.9	56.0	20.3	0.23	38.3
	GTV boost	59.1	56.5	61.9	56.6	20.3	0.24	37.6
	Replan	60.8	59.6	61.8	56.5	20.3	0.24	37.7
	RPTP	63.3	57.5	65.4	56.1	20.3	0.24	37.7
5	Clinical	61.5	56.6	62.6	60.7	17.7	0.12	46.7
	GTV boost	63.5	58.5	67.3	60.6	18.0	0.14	42.8
	Replan	63.7	54.8	65.7	60.8	17.7	0.13	41.0
	RPTP	66.4	58.2	70.6	59.3	18.0	0.14	42.4
Averaged difference		+6.2	+2.8	+10.8	0	+0.2	+0.01	−0.7
RPTP vs clinical
RPTP vs GTV boost		+3.4	+2.1	+3.9	−1.4	0	0	−0.1
RPTP vs replan		+1.8	+0.4	+5.7	−1.3	+0.1	0	+1.0

Abbreviations: GTV = gross tumor volume; NTCP = normal tissue complication probability; PTV = planning target volume; RPTP = robust predictive treatment planning.

The average differences between planning methods are shown in bold.