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Network of genes, proteins and their regulatory relationships related to PIA production in S. aureus and relevant in this proposal. Details described in the text. Lines ending in arrows (â ) indicate activation or induction while those ending with lines (⊥) indicate deactivation or repression. Biofilm-associated protein, Bap [53]; a-toxin, Hla [54]; protein A (SpA) [55]; aureolysin (Aur) and serine protease (SspA) [56].
