Table 1.
Characterization of amsacrine analog–loaded solid lipid nanoparticles (SLNs) in terms of the particle size, polydispersity index (PDI), zeta potential, and entrapment efficiency, and stability changes following storage at room temperature (25°C) for 1 month
| Formulation | Original | After 1 month |
|---|---|---|
| Particle diameter (nm) | 36.7±0.6 | 40.10±7.1 |
| PDI | 0.37±0.04 | 0.44±0.12 |
| Zeta potential (mV) | 34.5±4.7 | 37.4±3.2 |
| Entrapment efficiency (%) | 99.58±0.09 | 98.75±0.10 |
Note: Each value represents mean ± SD (n=3).
Abbreviation: SD, standard deviation.