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. 2016 Mar 10;12(3):e1005916. doi: 10.1371/journal.pgen.1005916

Fig 4. Cdkn1c promotes the browning of WAT in young mice.

Fig 4

(A) H&E of P7 WT, BACx1 and BACx2 rpWAT (WT from line BACx1). (B) Electron micrograph of WT and BACx1 P7 rpWAT (4000X). Mitochondria indicated by m and lipid by l. (C) QPCR analysis of Cdkn1c mRNA levels in P7 rpWAT from BACx1 and BACx2 relative to wild type controls. (D) QPCR of BAT-selective genes in WT, BACx1 and BACx2 P7 rpWAT. (E) Western blot analysis of UCP1, PRDM16 and β-ACTIN in P7 rpWAT from single litters of WT and BACx1 pups. Data expressed as mean ± SEM, t test. * P <0.05; ** P <0.01; *** P <0.005.