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. 2016 Mar 10;11(3):e0150819. doi: 10.1371/journal.pone.0150819

Table 1. Comparison of body temperature measurements: rectally by hand-held thermometer (core body temperature) versus imaging cage (surface body temperature) before and after allergen challenge in 2 different allergy mouse models.

Immunization group Core body temperature (°C) p-value Surface body temperature (°C) p-value
Before challenge After challenge 0 min after challenge 20 min after challenge
Casein-immunization experiment
PBS 38.20±0.26 37.97±0.25 n.s. 35.63±0.65 35.52±0.29 n.s.
alum-casein 38.07±0.25 31.23±1.53 **** 32.7±1.39 29.6±0.36 **
OVA-immunization experiment
Naive 36.98±0.43 37.68±0.55 n.s. 32.35±0.64 32.85±0.49 n.s.
alum-OVA 36.16±0.69 30.58±1.03 **** 31.46±0.68 28.12±0.36 ****

Values represent means±SD of group. P-values for statistical analysis of means of groups before vs. after challenge are shown.

****P <0.0001

**P<0.01, n.s. = not statistically significant.