Table 1. Comparison of body temperature measurements: rectally by hand-held thermometer (core body temperature) versus imaging cage (surface body temperature) before and after allergen challenge in 2 different allergy mouse models.
Immunization group | Core body temperature (°C) | p-value | Surface body temperature (°C) | p-value | ||
---|---|---|---|---|---|---|
Before challenge | After challenge | 0 min after challenge | 20 min after challenge | |||
Casein-immunization experiment | ||||||
PBS | 38.20±0.26 | 37.97±0.25 | n.s. | 35.63±0.65 | 35.52±0.29 | n.s. |
alum-casein | 38.07±0.25 | 31.23±1.53 | **** | 32.7±1.39 | 29.6±0.36 | ** |
OVA-immunization experiment | ||||||
Naive | 36.98±0.43 | 37.68±0.55 | n.s. | 32.35±0.64 | 32.85±0.49 | n.s. |
alum-OVA | 36.16±0.69 | 30.58±1.03 | **** | 31.46±0.68 | 28.12±0.36 | **** |
Values represent means±SD of group. P-values for statistical analysis of means of groups before vs. after challenge are shown.
****P <0.0001
**P<0.01, n.s. = not statistically significant.