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. 2016 Mar 10;11(3):e0151289. doi: 10.1371/journal.pone.0151289

Fig 4. PIEZO1 split protein produces currents from outside-out patches.

Fig 4

Panel A show that by increasing pressure on outside-out patches is correlated with increasing current. Panel B is a Boltzmann plot of current as a function of increasing pressure (n = 6, error bars are the S.D). The slope was approximately 8.6 mmHg-1 and P1/2 = 34 mmHg, close to wild type values of 8.1 mmHg-1 and 42 mmHg, respectively. Panel C is the current at the indicated voltages and Panel D is a plot of the IV curve showing that the reversal potential for the outside-out patch was ~ 0 mV.