Table 3. Distribution of haplotypes frequencies for CTLA4 gene polymorphisms (+49A/G and CT60A/G) among autoimmune hypothyroidism patients and controls.

	Case (freq) (n = 96)	Control (freq) (n = 120)	Chi2	P for association	P (global)	Odds ratio (95% CI)
A A	17(0.182)	34(0.287)	3.217	0.072945	<0.0001	0.553 [0.288~1.061]
A G	25(0.255)	48(0.396)	4.761	0.029157		0.523 [0.291~0.940]
G A	6(0.057)	17(0.138)	3.765	0.052383		0.381 [0.140~1.040]
G G	48(0.505)	21(0.179)	25.933	<0.0001		4.688 [2.534~8.670]