Table 2. Prediction of MbaA and MbaB adenylation domains specificities in B. xenovorans LB400 based on literature [16,17,27].
Stachelhaus-code residues | Predicted substrate | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
A-Domain | 235 | 236 | 239 | 278 | 299 | 301 | 322 | 330 | 331 | 517 | |
A1 | D | V | E | T | L | G | G | I | S | K | hfOrn/hαfOrn/hOrn/Phe |
A4 | D | G | E | Y | T | G | G | I | T | K | hfOrn |
A2 | D | L | T | K | V | G | H | V | G | K | β-OH-Asp |
A3 | D | V | W | H | V | S | L | I | D | K | Ser |