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. 2016 Mar 10;11(3):e0151031. doi: 10.1371/journal.pone.0151031

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© 2016 Grandclément et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — (A) Relative to untransfected control HEK293 cells (red line) stable hTRPA1 transfectants (blue line) respond to Bourgeonal, Oxa and DNFB and AITC. (B) The TRPA1 inhibitor HC0300301 (100 μM) inhibits Bourgeonal, Oxa and DNFB-induced Ca²⁺ flux response in HEK293 cells expressing hTRPA1 (green line). (C) The TRP1A inhibitor HC0300301 (100 μM) does not inhibit Oxa and DNFB-induced Ca²⁺ flux in NK cells. (D) Response of wild type (TRPA1^+/+) and TRPA1^-/- NK cells to Bourgeonal, Oxa and DNFB. n = 4 from 2 independent experiments.