Table 3. Summary of the serological datasets collected before the introduction of vaccination which were used to estimate the global burden of CRS.

	Africa	Americas	E Mediterranean	Europe	SE Asia	W Pacific
No. countries represented	13	12	9	13	4	8
No. of countries in region	47	39	22	51	11	27
Datasets from countries where RCV had not been introduced by 2010	Benin (1993); Congo (<1991); Cote d’Ivoire (1975, 1985–6); Ethiopia (1981, 1994); Gabon (1985); Ghana (1997); Kenya (1996–7); Madagascar (1990–5); Mozambique (2002); Nigeria (<1978, <2002, 2007–8); Senegal (1996–2001); South Africa (2003); Zambia (1979–80)	-	Pakistan (<1997, 1999–2004); Yemen (1985, 2002–3)		Bangladesh (2004–5); India (1968, 1968, 1972–3, 1972–3, 1976, <1987, <1990, 1999–2000); Nepal (2008)	Vietnam (2009–10)
# datasets (# with SS+ >1000)	17 (7)	-	4 (2)	-	10 (3)	1 (1)
Datasets from countries where RCV had been introduced by 2010	-	Argentina (1967–8,1967–8); Brazil (1967–8,1987); Canada (<1967); Chile (1967–8,1967–8); Haiti (2002); Jamaica (1967–8,1967–8); Mexico (1987–8,1989); Panama (1967–8,1967–8); Peru (1967–8,2003); Trinidad (1966–7,1967–8); Uruguay (1967–8,1967–8); USA (<1967,<1967)	Bahrain (1981); Iran (1993–5); Jordan (1982–3); Kuwait (<1978); Lebanon (1980–1); Morocco (1969–70); Saudi Arabia (1989, 1992–3); Tunisia (<1970)	Czech Republic (<1967); Denmark (<1967,1983); Germany (1990); England (<1967,1986–7); Finland (1979); France (<1967); Kyrgyzstan (2001); Romania (<1989); Turkey (1998,2003–4)	Thailand (1978)	Australia (<1967?); China (1979–80); Fiji (<1973); Japan (<1967, <1967); Malaysia (<1972); Singapore (1975–9); Taiwan (1984,1984–6)
# datasets (# with SS+ >1000)	-	22 (4)	9 (5)	13 (4)	1 (0)	9 (4)

* The year in which the study was carried out is not known for several studies. For these studies, the table includes “<” followed by the year of publication.

⁺ SS = sample size.