Table 2.
Crosses of inbred strains and F1 hybridsa
| F1 hybrid cross; two abnormal strains | Crosses involving BTBR and I/Ln | 3-way; all abnormal strains (no BALB) [84] |
|---|---|---|
| 129 x BALB* [52] | (BTBR x I/Ln) x BTBR* [24] | 50% 129 alleles [9] |
| 129 x BTBR* [35] | (BTBR x I/Ln) F2 [55] and F3 [17] | 50% BTBR alleles [58] |
| 129 x I/Ln [20] | 3-way cross; 25% C57 alleles | 50% I/Ln alleles [17] |
| BALB x BTBR* [33] | (C57 x 129) x BALB* [32] | 3-way; all abnormal strains (no BTBR) [66] |
| BALB x I/Ln [17] | (C57 x 129) x BTBR* [16] | 50% 129 alleles [10] |
| BTBR x I/Ln [19] | (C57 x 129) x I/Ln [32] | 50% BALB alleles [20] |
| F1 hybrid cross; C57 x abnormal strain | (BALB x C57) x BTBR [17] | 50% I/Ln alleles* [36] |
| C57 x 129 [12] | (BALB x C57) x I/Ln [22] | 3-way; all abnormal strains (no I/Ln) [69] |
| C57 x BALB* [12] | 3-way; all abnormal strains (no 129) [72] | 50% 129 alleles; (BALB x BTBR) x 129 [32] |
| C57 x BTBR [12] | 50% BALB alleles* [30] | 50% BALB alleles; (129 x BTBR) x BALB [17] |
| C57 x I/Ln [21] | 50% BTBR alleles* [20] | 50% BTBR alleles; (129 x BALB) x BTBR [20] |
| Backcross involving C57 | 50% I/Ln alleles* [22] | 4-way cross among all abnormal strains [46] |
| (C57 x 129) x 129 [15] | (BALB x BTBR) x (129 x I/Ln) [35] | |
| (C57 x BALB) x BALB [18] | (BALB x I/Ln) x (129 x BTBR) [11] | |
| (C57 x BTBR) x BTBR* [29] |
a
Sample sizes in brackets. Abbreviations: 129, 129S1/SvImJ; BALB, BALB/cJ; BTBR, BTBR T+ tfJ; C57, C57BL/6J; I/Ln, I/LnJ. Genotype of female parent is given first; e.g., BTBR x I/Ln is BTBR female mated with I/Ln male. (BALB x I/Ln) x (129 x BTBR) 4-way cross is (BALB x I/Ln) female by (129 x BTBR) male.
Asterisk (*) indicates data combined from more than one specific cross, reciprocal crosses in most cases.