| Group 1 | Group 2 | Effect size d | A priori power | Group 1 sample size |
Group 2 sample size |
|---|---|---|---|---|---|
| siNC | siSER | 3.61647 | 81.9% | 4 | 4 |
| siNC | siZNF | 0.9329 | 80.2%2 | 302 | 302 |
| siNC | siVAPA | 7.63300 | 98.5%1 | 31 | 31 |
| siNC | siCNO | 4.27377 | 93.2% | 4 | 4 |
| siNC | siPTEN | 12.0568 | 99.9%1 | 31 | 31 |
1 4 samples per group will be used making the power >99.9%.
2 A sensitivity calculation was performed since the original data showed a non-significant effect. The effect size that can be detected with 80% power and a sample size n=4 per group is 3.5378.