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. 2016 Mar 1;5:e12470. doi: 10.7554/eLife.12470
Group 1 Group 2 Effect size d A priori power Group 1
sample size
Group 2 sample size
siNC siSER 3.61647 85.8% 4 4
siNC siZNF 0.9329 80.8%2 292 292
siNC siVAPA 7.63300 99.4%1 31 31
siNC siCNO 4.27377 95.4% 4 4
siNC siPTEN 12.0568 99.9%1 31 31

1 4 samples per group will be used making the power >99.9%.

2 A sensitivity calculation was performed since the original data showed a non-significant effect. The effect size that can be detected with 80% power and a sample size n=4 per group is 3.3711.