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. 2016 Mar 11;6:59. doi: 10.3389/fonc.2016.00059

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Copyright © 2016 Serrao and Brindle.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Imaging prostate cancer with hyperpolarized [1-¹³C]pyruvate. The T₂-weighted image of a patient with biopsy-proven bilateral prostate cancer showed only a unilateral decrease in signal intensity. However, the metabolic image ([1-¹³C]lactate/[1-¹³C]pyruvate ratio) detected disease on both the right and left sides of the prostate. Reproduced from Nelson et al. (3) with permission.