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. 2016 Mar 11;8:51. doi: 10.3389/fnagi.2016.00051

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Copyright © 2016 Li, Liu, Qiu, Ren, Dai, Deng and Qing.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Detection of related small peptide species of Aβ. (A) The chromatographys of IAT standard peptides. (B) The Intensity of multiple reactions monitoring (MRM) ion chromatography of ITA. (1) Its transition is m/z = 303.7/185. Black, pCDNA4.1; Red, PS1; Blue, M233V. (C) The chromatographys of VVIA standard peptides. (D) The Intensity of multiple reactions monitoring (MRM) ion chromatography of VVIA. (2) Its transition is m/z = 401.2/171.1. Black, pCDNA4.1; Red, PS1; Blue, M233V. (E) Aβ species in lysates of 2EB2 cells in a 10 cm dish overexpressing PS1 WT.