Table 2. Biodistribution of AgNPs and AgNP-MSA in different tissues of treated LACA mice; the result was obtained from ICP–AES analysis.

	Liver		Spleen		Kidney
Dose (mg/kg b.w.)	AgNPs	AgNP-MSA	AgNPs	AgNP-MSA	AgNPs	AgNP-MSA
1	0.021±0.01 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
2	0.467±0.23 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
3	1.67±0.13 ppm	<0.01 ppm	0.027±0.003 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
4	2.4745±0.16 ppm	<0.01 ppm	0.079±0.007 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
5	2.7612±0.325 ppm	<0.01 ppm	0.0854±0.0025 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
6	2.8732±0.47 ppm	<0.01 ppm	0.0873±0.0047 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
7	2.8709±0.387 ppm	<0.01 ppm	0.09921±0.0037 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
8	3.1557±0.7634 ppm	<0.01 ppm	0.117±0.0064 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
9	3.113±0.023 ppm	<0.01 ppm	0.14±0.003 ppm	<0.01 ppm	<0.01 ppm	<0.01 ppm
10	3.421±0.12 ppm	0.03±0.053 ppm	0.131±0.017 ppm	0.03±0.053 ppm	0.0221±0.002 ppm	<0.01 ppm

Abbreviations: AgNP, silver nanoparticle; ICP–AES, inductively coupled plasma–atomic emission spectroscopy; MSA, mouse serum albumin.