Table 3. Blood toxicity profile of AgNP-MSA-treated LACA albino mice. The results are expressed as the mean±standard error mean (P<0.001).
| Parameters | Control | 9 mg/kg b.w. | 10 mg/kg b.w. |
|---|---|---|---|
| RBC (×1012/l) | 14.162±1.12 | 11.264±0.51 | 9.77±0.34** |
| MCV (fl) | 46.954±0.85 | 46.9±1.31 | 48.32±1.33 |
| RDW (%) | 15.58±1.027 | 15.14±0.65 | 13.284±1.37 |
| HCT (%) | 51.52±1.75 | 46.286±1.28 | 48.274±1.29 |
| PLT (×109/l) | 673±12.77 | 549.8±17.64 | 793.8±20.28 |
| MPV (fl) | 5.792±0.19 | 6.128±0.088 | 6.174±0.24 |
| PDW (fl) | 8.946±0.16 | 9.858±0.28 | 9.372±0.32 |
| PCT (%) | 0.452±0.02 | 0.312±0.05 | 0.484±0.02 |
| HGB (g/dl) | 16.74±0.67 | 10.77±1.21 | 10.32±0.71 |
| MCH (pg) | 16.98±0.44 | 12.44±0.53 | 15.348±0.33 |
| MCHC (g/dl) | 32.82±0.94 | 28.088±0.53 | 32.522±1.20 |
Abbreviations: AgNP, silver nanoparticle; HCT, hematocrit; HGB, hemoglobin; MCA, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin content; MPV, mean platelet volume; MSA, mouse serum albumin; PCT, procalcitonin; PDW, platelet distribution width; PLT, platelet count; RBC, red blood cell count; RDW, RBC distribution width.